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Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules. All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), Axin-1, beta-catenin, and glycogen synthase kinase 3 beta. Formation of this complex leads to phosphorylation of beta-catenin and down-regulation of beta-catenin activity. A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together. Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: Axin-APC-beta-catenin-GSK3B complex
Acc: GO:0034747
Aspect: Cellular Component
Desc: A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), Axin-1, beta-catenin, and glycogen synthase kinase 3 beta. Formation of this complex leads to phosphorylation of beta-catenin and down-regulation of beta-catenin activity.
Proteins in PDR annotated with:
   This term: 4 [Search]
   Term or descendants: 4 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0034747 - Axin-APC-beta-catenin-GSK3B complex (interactive image map)

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