YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

The hydrolysis of a peptide bond or bonds within a protein as part of protein maturation, the process leading to the attainment of the full functional capacity of a protein. Any process that modulates the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process whereby plasminogen is processed to plasmin. Any process that increases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process whereby plasminogen is processed to plasmin. The process whereby inactive plasminogen is processed to active plasmin. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide. Any process that decreases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process whereby plasminogen is processed to plasmin. The proteolytic processing of an inactive enzyme to an active form.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: plasminogen activation
Acc: GO:0031639
Aspect: Biological Process
Desc: The process whereby inactive plasminogen is processed to active plasmin. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide.
Synonyms:
  • cleavage of plasminogen to plasmin
Proteins in PDR annotated with:
   This term: 8 [Search]
   Term or descendants: 13 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0031639 - plasminogen activation (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle