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Cleavage of the 5'-cap of a nuclear-transcribed mRNA that is independent of poly(A) tail shortening. The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 5'-cap. A pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of steps that is independent of deadenylation, but requires decapping followed by transcript decay, and that can regulate mRNA stability. The chemical reactions and pathways resulting in the breakdown of nuclear-transcribed mRNAs in eukaryotic cells. The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: nuclear-transcribed mRNA catabolic process, deadenylation-independent decay
Acc: GO:0031086
Aspect: Biological Process
Desc: A pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of steps that is independent of deadenylation, but requires decapping followed by transcript decay, and that can regulate mRNA stability.
Synonyms:
  • mRNA catabolism, deadenylation-independent
  • mRNA breakdown, deadenylation-independent decay
  • deadenylation-independent mRNA decay
  • mRNA catabolism, deadenylylation-independent
  • mRNA catabolic process, deadenylation-independent
  • mRNA catabolism, deadenylation-independent decay
  • nuclear mRNA catabolic process, deadenylation-independent decay
  • mRNA catabolic process, deadenylylation-independent
  • deadenylylation-independent mRNA decay
  • mRNA degradation, deadenylation-independent decay
Proteins in PDR annotated with:
   This term: 1 [Search]
   Term or descendants: 13 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0031086 - nuclear-transcribed mRNA catabolic process, deadenylation-independent decay (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle