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The cell cycle process where a cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place. Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals. Any process involved in the progression from anaphase/telophase to G1 that is associated with a conversion from high to low mitotic CDK activity. Any process that activates or increases the frequency, rate or extent of septation initiation signaling. A series of molecular signals within the cell that are mediated by a member of the Ras superfamily of proteins switching to a GTP-bound active state. Any process that stops, prevents or reduces the frequency, rate or extent of septation initiation signaling. Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Any process that modulates the frequency, rate or extent of contraction of the actomyosin ring involved in cytokinesis that takes place as part of a cell cycle. Any process that modulates the frequency, rate or extent of septation initiation signaling. The series of molecular signals, mediated by the small GTPase Ras, that results in the initiation of contraction of the contractile ring, at the beginning of cytokinesis and cell division by septum formation. The pathway coordinates chromosome segregation with mitotic exit and cytokinesis. Any process that modulates the rate or extent of progress through the mitotic cell cycle. The aggregation, arrangement and bonding together of a cellular component. Any process that modulates the frequency, rate or extent of a cytokinetic process. The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. The progeny cells that form a barrier septum are not able to exchange intracellular material. The process of an actomyosin ring getting smaller in diameter, in the context of cytokinesis that takes place as part of a cell cycle. A cellular process that is involved in the division of the cytoplasm of a cell and its separation into two daughter cells.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: septation initiation signaling
Acc: GO:0031028
Aspect: Biological Process
Desc: The series of molecular signals, mediated by the small GTPase Ras, that results in the initiation of contraction of the contractile ring, at the beginning of cytokinesis and cell division by septum formation. The pathway coordinates chromosome segregation with mitotic exit and cytokinesis.
Synonyms:
  • septation initiation network
  • septation initiation signalling
  • SIN
Proteins in PDR annotated with:
   This term: 10 [Search]
   Term or descendants: 22 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0031028 - septation initiation signaling (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle