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Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice. Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules. Any of several large complexes that contain two or three dynein heavy chains and several light chains, and have microtubule motor activity. Any multimeric complex connected to a microtubule. The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins. A dynein complex found in eukaryotic cilia and flagella; the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion. May contain two or three dynein heavy chains as well as several light chains. Any dynein complex that catalyzes movement along a cytoplasmic microtubule; cytoplasmic dynein complexes participates in many transport activities in eukaryotes, such as mRNA localization, intermediate filament transport, nuclear envelope breakdown, apoptosis, transport of centrosomal proteins, mitotic spindle assembly, virus transport, kinetochore functions, and movement of signaling and spindle checkpoint proteins. Subunits associated with the dynein heavy chain mediate association between dynein heavy chain and cargoes,and may include light chains and light intermediate chains.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: dynein complex
Acc: GO:0030286
Aspect: Cellular Component
Desc: Any of several large complexes that contain two or three dynein heavy chains and several light chains, and have microtubule motor activity.
Proteins in PDR annotated with:
   This term: 95 [Search]
   Term or descendants: 138 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0030286 - dynein complex (interactive image map)
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