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Any process that stops, prevents or reduces the frequency, rate or extent of B cell differentiation. Any process that modulates the frequency, rate or extent of B cell differentiation. The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor. The process dependent upon B cell antigen receptor signaling in response to self or foreign antigen through which B cells are selected for survival. Any process that activates or increases the frequency, rate or extent of B cell differentiation. The process whereby transitional stage B cells acquire the specialized features of mature B cells in the spleen. The process whereby a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a plasmacytoid dendritic cell or any cell of the myeloid leukocyte or lymphocyte lineages. The process whereby a precursor cell type acquires the specialized features of a B cell. The process whereby a relatively unspecialized precursor cell acquires specialized features of B cells, T cells, or natural killer cells. The process whereby a precursor cell type acquires the specialized features of an immature B cell. The process whereby a lymphoid progenitor cell becomes committed to become any type of B cell.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: B cell differentiation
Acc: GO:0030183
Aspect: Biological Process
Desc: The process whereby a precursor cell type acquires the specialized features of a B cell.
Synonyms:
  • B-cell differentiation
  • B-lymphocyte differentiation
  • B lymphocyte differentiation
  • GO:0042115
Proteins in PDR annotated with:
   This term: 53 [Search]
   Term or descendants: 97 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0030183 - B cell differentiation (interactive image map)

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