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The directed orientation of natural killer cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with a cell displaying natural killer cell activating ligands. A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor. A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor. The change in morphology and behavior of a natural killer cell in response to a cytokine, chemokine, cellular ligand, or soluble factor. Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation. Any process that modulates the frequency, rate or extent of natural killer cell activation. The expansion of a natural killer cell population by cell division. The process whereby a relatively unspecialized cell acquires the specialized features of a natural killer cell. Any process that activates or increases the frequency, rate or extent of natural killer cell activation. The change in morphology and behavior of a natural killer cell resulting from exposure a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: natural killer cell activation
Acc: GO:0030101
Aspect: Biological Process
Desc: The change in morphology and behavior of a natural killer cell in response to a cytokine, chemokine, cellular ligand, or soluble factor.
Synonyms:
  • NK cell activation
Proteins in PDR annotated with:
   This term: 13 [Search]
   Term or descendants: 36 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0030101 - natural killer cell activation (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle