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The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates. Any process that modulates the frequency, rate or extent of lymphocyte differentiation. A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor. A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor. The process by which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex. The process whereby a precursor cell type acquires the specialized features of a B cell. The process whereby a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a plasmacytoid dendritic cell or any cell of the myeloid leukocyte or lymphocyte lineages. The process whereby a relatively unspecialized precursor cell acquires specialized features of B cells, T cells, or natural killer cells. The process whereby a relatively unspecialized cell acquires the specialized features of a natural killer cell. Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation. Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte differentiation. The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: lymphocyte differentiation
Acc: GO:0030098
Aspect: Biological Process
Desc: The process whereby a relatively unspecialized precursor cell acquires specialized features of B cells, T cells, or natural killer cells.
Synonyms:
  • lymphocyte cell differentiation
  • lymphocytic blood cell differentiation
  • GO:0046650
Proteins in PDR annotated with:
   This term: 12 [Search]
   Term or descendants: 268 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0030098 - lymphocyte differentiation (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle