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Catalysis of the transfer of carbohydrate from one side of the membrane to the other. Catalysis of the transfer of a polyol from one side of the membrane to the other. A polyol is any polyhydric alcohol. Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor). Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + mannitol(out) = protein histidine + mannitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. Catalysis of the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction. Catalysis of the transfer of mannitol from one side of the membrane to the other. Mannitol is the alditol derived from D-mannose by reduction of the aldehyde group. Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sugar(out) = protein histidine + sugar phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity
Acc: GO:0022872
Aspect: Molecular Function
Desc: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + mannitol(out) = protein histidine + mannitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
Synonyms:
  • mannitol PTS transporter activity
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0022872 - protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity (interactive image map)
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