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The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened in granule cells that contributes to the regulation of proliferation of the cells. The process that mediates the transfer of information from Purkinje cells to granule cell precursors resulting in an increase in rate of granule cell precursor cell proliferation. Any process that mediates the transfer of information from one cell to another. The process that activates or increases the rate or extent of granule cell precursor proliferation. Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell. The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: smoothened signaling pathway involved in regulation of granule cell precursor cell proliferation
Acc: GO:0021938
Aspect: Biological Process
Desc: The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened in granule cells that contributes to the regulation of proliferation of the cells.
Synonyms:
  • hedgehog signaling pathway involved in regulation of granule cell precursor cell proliferation
  • hh signaling pathway involved in regulation of granule cell precursor cell proliferation
  • smoothened signalling pathway in regulation of granule cell precursor cell proliferation
Proteins in PDR annotated with:
   This term: 7 [Search]
   Term or descendants: 7 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0021938 - smoothened signaling pathway involved in regulation of granule cell precursor cell proliferation (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle