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The chemical reactions and pathways involving lactate, the anion of lactic acid. The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-). The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into D-lactate via the intermediate S-lactoyl-glutathione. Glutathione is used in the first step of the pathway and then regenerated in the second step. The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid. The chemical reactions and pathways resulting in the breakdown of aldehydes, any organic compound with the formula R-CH=O. The chemical reactions and pathways resulting in the formation of D-lactate from other compounds, including methylglyoxal, via the intermediate (R)-lactaldehyde. The chemical reactions and pathways involving methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: methylglyoxal catabolic process to D-lactate
Acc: GO:0019243
Aspect: Biological Process
Desc: The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into D-lactate via the intermediate S-lactoyl-glutathione. Glutathione is used in the first step of the pathway and then regenerated in the second step.
Synonyms:
  • methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione
  • methylglyoxal degradation to D-lactate
  • D-lactate biosynthesis from methylglyoxal
  • D-lactate biosynthetic process from methylglyoxal
  • methylglyoxal breakdown to D-lactate
  • methylglyoxal catabolism to D-lactate via S-lactoyl-glutathione
  • glyoxalase system
  • methylglyoxal detoxification
Proteins in PDR annotated with:
   This term: 15 [Search]
   Term or descendants: 15 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0019243 - methylglyoxal catabolic process to D-lactate (interactive image map)

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