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Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules. The lipid bilayer surrounding the endoplasmic reticulum. A multiprotein complex at least composed of serine palmitoyltransferases and ORM proteins (known as ORMDL proteins in mammals and other higher vertebrates) that plays a key role in sphingolipid homeostasis. A dimeric complex of the endoplasmic reticulum that catalyzes S-palmitoylation, the addition of palmitate (C16:0) or other long-chain fatty acids to proteins at a cysteine residue. Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. An enzyme complex that catalyzes the transfer of a palmitoyl on to serine, forming 3-dehydro-D-sphinganine.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: serine C-palmitoyltransferase complex
Acc: GO:0017059
Aspect: Cellular Component
Desc: An enzyme complex that catalyzes the transfer of a palmitoyl on to serine, forming 3-dehydro-D-sphinganine.
Proteins in PDR annotated with:
   This term: 14 [Search]
   Term or descendants: 15 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0017059 - serine C-palmitoyltransferase complex (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle