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Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules. A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together. Any constituent part of a cell, the basic structural and functional unit of all organisms. The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together. A large protein complex, containing 12-15 subunits, that spans the cell envelope of Gram-negative bacteria and mediates the movement of proteins into the extracellular environment. The complex includes a component in the cytoplasm, an inner membrane subcomplex that reaches into the periplasmic compartment and a secretion pore in the outer membrane. Proteins using the Type II pathway are transported across the cytoplasmic membrane by the Sec or Tat complex.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: type II protein secretion system complex
Acc: GO:0015627
Aspect: Cellular Component
Desc: A large protein complex, containing 12-15 subunits, that spans the cell envelope of Gram-negative bacteria and mediates the movement of proteins into the extracellular environment. The complex includes a component in the cytoplasm, an inner membrane subcomplex that reaches into the periplasmic compartment and a secretion pore in the outer membrane. Proteins using the Type II pathway are transported across the cytoplasmic membrane by the Sec or Tat complex.
Synonyms:
  • main terminal branch
  • T2SS-associated complexes
  • Sec-dependent secretion system-associated complex
  • MTB
  • general secretion pathway-associated complex
Proteins in PDR annotated with:
   This term: 55 [Search]
   Term or descendants: 55 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0015627 - type II protein secretion system complex (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle