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A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective. The enlargement or overgrowth of all or part of an organ due to an increase in size of muscle cells without cell division. In the case of striated muscle, this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils. Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hypertrophy. The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy. The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development. The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells as a result of a disturbance in organismal or cellular homeostasis. Any process that modulates the frequency, rate or extent of muscle hypertrophy. Any process that activates or increases the frequency, rate or extent of muscle hypertrophy. The enlargement or overgrowth of all or part of an organ due to an increase in size of its smooth muscle cells without cell division. Physiological hypertrophy is a normal process during development, and can also occur in mature structures on demand. In the uterus, smooth muscle cells undergo hypertrophy during pregnancy. A organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: muscle hypertrophy
Acc: GO:0014896
Aspect: Biological Process
Desc: The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy.
Proteins in PDR annotated with:
   This term: 5 [Search]
   Term or descendants: 20 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0014896 - muscle hypertrophy (interactive image map)

YRC Informatics Platform - Version 3.0
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