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Any process that modulates the frequency, rate or extent of the regulated release of serotonin. The regulated release of serotonin by a cell or group of cells. Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine synthesised in serotonergic neurons in the central nervous system, enterochromaffin cells in the gastrointestinal tract and some immune system cells. Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or group of cells. Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. The process whereby a signal is secreted or discharged into the extracellular medium from a cellular source. Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of a substance from a cell or group of cells. Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. The controlled release of a substance by a cell, a group of cells, or a tissue. Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of serotonin. Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of, within or between cells by means of some external agent such as a transporter or pore. Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of amines into, out of, within or between cells by means of some external agent such as a transporter or pore. Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of, within or between cells by means of some external agent such as a transporter or pore. The controlled release of a substance by a cell. Any process that modulates the frequency, rate or extent of a process by which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell. Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. The directed movement of serotonin into, out of, within or between cells by means of some external agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems. Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells by means of some external agent such as a transporter or pore.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: negative regulation of serotonin secretion
Acc: GO:0014063
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of serotonin.
Synonyms:
  • down regulation of serotonin secretion
  • inhibition of serotonin secretion
  • downregulation of serotonin secretion
  • down-regulation of serotonin secretion
Proteins in PDR annotated with:
   This term: 7 [Search]
   Term or descendants: 7 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0014063 - negative regulation of serotonin secretion (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle