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The process by which glial cells are generated. This includes the production of glial progenitors and their differentiation into mature glia. The process whereby a relatively unspecialized cell acquires the specialized features of a Schwann cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function. Any process that modulates the frequency, rate or extent of Schwann cell differentiation. Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell differentiation. Any process that activates or increases the frequency, rate or extent of Schwann cell differentiation. The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands. The process aimed at the progression of a Schwann cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function. The process whereby a relatively unspecialized cell acquires the specialized features of a glial cell. The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process. The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: Schwann cell differentiation
Acc: GO:0014037
Aspect: Biological Process
Desc: The process whereby a relatively unspecialized cell acquires the specialized features of a Schwann cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function.
Proteins in PDR annotated with:
   This term: 11 [Search]
   Term or descendants: 24 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0014037 - Schwann cell differentiation (interactive image map)

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