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Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate. Catalysis of the reaction: a 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. Catalysis of the reaction: a nucleotide + H2O = a nucleoside + phosphate. Catalysis of the reaction: 5'-IMP + H2O = inosine + phosphate. Catalysis of the reaction: 5'-GMP + H2O = guanosine + phosphate.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: 5'-nucleotidase activity
Acc: GO:0008253
Aspect: Molecular Function
Desc: Catalysis of the reaction: a 5'-ribonucleotide + H2O = a ribonucleoside + phosphate.
Synonyms:
  • 5'-mononucleotidase activity
  • AMPase
  • 5'-adenylic phosphatase
  • adenosine 5'-phosphatase
  • AMP phosphohydrolase
  • snake venom 5'-nucleotidase
  • 5' nucleotidase activity
  • adenosine monophosphatase
  • uridine 5'-nucleotidase
  • 5'-AMP nucleotidase
  • 5'-AMPase
  • UMPase
  • AMP phosphatase
  • thimidine monophosphate nucleotidase
  • 5'-ribonucleotide phosphohydrolase activity
Proteins in PDR annotated with:
   This term: 42 [Search]
   Term or descendants: 45 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0008253 - 5'-nucleotidase activity (interactive image map)
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