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A series of molecular signals in which a cell uses a phosphoinositide to convert an extracellular signal into a response. The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by the activation of phospholipase C and the subsequent release of inositol trisphosphate. The initiation of the activity of the inactive enzyme phospolipase C as the result of a series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand. The series of molecular signals generated as a consequence of a metabotropic glutamate receptor binding to its physiological ligand, followed by the activation of phospholipase C and the subsequent release of inositol trisphosphate. Any process that increases the rate of phospholipase C activity. A signaling pathway that results in preventing the activation of phospholipase C in response to a signal. The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand. The series of molecular signals generated as a consequence of a tachykinin receptor binding to its physiological ligand, followed by the activation of phospholipase C and the subsequent release of inositol trisphosphate. A series of molecular signals in which an ion or small molecule is formed or released into the cytosol, thereby helping relay the signal within the cell. The series of molecular signals generated as a consequence of a serotonin receptor binding to its physiological ligand, followed by the activation of phospholipase C and the subsequent release of inositol trisphosphate. Any process that increases the concentration of calcium ions in the cytosol that contributes to the process of G-protein signaling coupled to IP3 second messenger. The series of molecular signals generated as a consequence of a muscarinic acetylcholine receptor binding to its physiological ligand, followed by the activation of phospholipase C and the subsequent release of inositol trisphosphate. The series of molecular signals generated as a consequence of a dopamine receptor binding to its physiological ligand, followed by the activation of phospholipase C and the subsequent release of inositol trisphosphate. The series of molecular signals generated as a consequence of light impinging on rhodopsin molecules in a photoreceptor cell, followed by the activation of phospholipase C and the subsequent release of inositol trisphosphate. Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
Acc: GO:0007200
Aspect: Biological Process
Desc: The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by the activation of phospholipase C and the subsequent release of inositol trisphosphate.
Synonyms:
  • G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)
  • G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)
  • G protein signaling, coupled to IP3 second messenger (phospholipase C activating)
  • phospholipase C-activating dopamine receptor signaling pathway
  • G protein signalling, coupled to IP3 second messenger (phospholipase C activating)
Proteins in PDR annotated with:
   This term: 53 [Search]
   Term or descendants: 109 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0007200 - activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger (interactive image map)
YRC Informatics Platform - Version 3.0
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