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Any process that stops or reduces the rate of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. The series of molecular signals generated as a consequence of a serotonin receptor binding to its physiological ligand, followed by inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP. The series of molecular signals generated as a consequence of a muscarinic acetylcholine receptor binding to its physiological ligand, followed by inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP. The series of molecular signals generated as a consequence of a metabotropic glutamate receptor binding to its physiological ligand, followed by inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP. The series of molecular signals generated as a consequence of a dopamine receptor binding to its physiological ligand, followed by inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP. Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase activity. The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP. The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by modulation of a nucleotide cyclase activity and a subsequent change in the concentration of a cyclic nucleotide. A series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response. The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by modulation of adenylyl cyclase activity and a subsequent change in the concentration of cyclic AMP. Any process that modulates the frequency, rate or extent of adenylate cyclase activity. The series of molecular signals generated as a consequence of an opioid receptor binding to its physiological ligand, followed by inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP. Any process that stops or reduces the activity of a cyclase.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: inhibition of adenylate cyclase activity by G-protein signaling pathway
Acc: GO:0007193
Aspect: Biological Process
Desc: The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP.
Synonyms:
  • G protein signaling, adenylate cyclase inhibiting pathway
  • G-protein signaling, adenylate cyclase inhibiting pathway
  • G protein signalling, adenylyl cyclase inhibiting pathway
  • G protein signaling, adenylyl cyclase inhibiting pathway
  • G protein signalling, adenylate cyclase inhibiting pathway
  • G-protein signalling, adenylate cyclase inhibiting pathway
  • G-protein signalling, adenylyl cyclase inhibiting pathway
  • G-protein signaling, adenylyl cyclase inhibiting pathway
Proteins in PDR annotated with:
   This term: 50 [Search]
   Term or descendants: 71 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0007193 - inhibition of adenylate cyclase activity by G-protein signaling pathway (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle