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Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins. The actin filament-based process by which cytoplasmic actin filaments slide past one another resulting in contraction of all or part of the cell body. The orderly movement of a cell from one site to another, often during the development of a multicellular organism or multicellular structure. The orderly movement of a cell from one site to another along a substrate such as the extracellular matrix; the migrating cell forms a protrusion that attaches to the substrate. Cell migration that is accomplished by extension and retraction of a pseudopodium. The translocation of the cell body forward during cell migration, mediated by tractional force on its substrate and tension in the cortical cytoskeleton. Adhesions transmit propulsive forces and serve as traction points over which the cell moves.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: substrate-bound cell migration, cell contraction
Acc: GO:0006932
Aspect: Biological Process
Desc: The translocation of the cell body forward during cell migration, mediated by tractional force on its substrate and tension in the cortical cytoskeleton. Adhesions transmit propulsive forces and serve as traction points over which the cell moves.
Proteins in PDR annotated with:
   This term: 4 [Search]
   Term or descendants: 4 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0006932 - substrate-bound cell migration, cell contraction (interactive image map)
YRC Informatics Platform - Version 3.0
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