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A G-protein coupled receptor that preferentially binds endothelin 1. Combining with an extracellular or intracellular peptide to initiate a change in cell activity. A receptor that binds an extracellular ligand and transmits the signal to a heterotrimeric G-protein complex. These receptors are characteristically seven-transmembrane receptors and are made up of hetero- or homodimers. Combining with endothelin to initiate a change in cell activity. Combining with an extracellular or intracellular peptide to initiate a G-protein mediated change in cell activity. A G-protein is a signal transduction molecule that alternates between an inactive GDP-bound and an active GTP-bound state. A G-protein coupled receptor that binds all endothelin molecules with approximately equal affinity.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: endothelin receptor activity
Acc: GO:0004962
Aspect: Molecular Function
Desc: Combining with endothelin to initiate a change in cell activity.
Proteins in PDR annotated with:
   This term: 14 [Search]
   Term or descendants: 14 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004962 - endothelin receptor activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle