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Catalysis of the reaction: S-adenosyl-L-methionine + protein C-terminal S-farnesyl-L-cysteine = S-adenosyl-L-homocysteine + protein C-terminal S-farnesyl-L-cysteine methyl ester. Catalysis of the transfer of a methyl group to an acceptor molecule. Catalysis of the transfer of a methyl group to the carbon atom of the C-terminal residue of a protein. Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate. Catalysis of the transfer of a methyl group (CH3-) to a protein. Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: protein-S-isoprenylcysteine O-methyltransferase activity
Acc: GO:0004671
Aspect: Molecular Function
Desc: Catalysis of the reaction: S-adenosyl-L-methionine + protein C-terminal S-farnesyl-L-cysteine = S-adenosyl-L-homocysteine + protein C-terminal S-farnesyl-L-cysteine methyl ester.
Synonyms:
  • farnesyl-protein carboxymethyltransferase activity
  • S-adenosyl-L-methionine:protein-C-terminal-S-farnesyl-L-cysteine O-methyltransferase activity
  • protein C-terminal farnesylcysteine O-methyltransferase activity
  • farnesyl cysteine C-terminal methyltransferase activity
  • prenylated protein methyltransferase activity
  • isoprenylcysteine carboxylmethyltransferase activity
  • prenylcysteine carboxyl methyltransferase activity
  • isoprenylated protein methyltransferase activity
  • prenylcysteine carboxylmethyltransferase activity
  • S-farnesylcysteine methyltransferase activity
  • protein S-farnesylcysteine C-terminal methyltransferase activity
  • prenylcysteine carboxymethyltransferase activity
  • prenylcysteine methyltransferase activity
  • farnesylated protein C-terminal O-methyltransferase activity
  • GO:0018225
  • prenylated protein carboxyl methyltransferase activity
Proteins in PDR annotated with:
   This term: 11 [Search]
   Term or descendants: 11 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004671 - protein-S-isoprenylcysteine O-methyltransferase activity (interactive image map)

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