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Catalysis of the transfer of an acetyl group to a nitrogen atom on the acceptor molecule. Catalysis of the acetylation of the N-terminal amino acid residue of a peptide or protein, according to the reaction: acetyl-CoA + peptide = CoA + N-alpha-acetylpeptide. Catalysis of the reaction: acetyl-CoA + ribosomal-protein L-alanine = CoA + ribosomal-protein N-acetyl-L-alanine. Catalysis of the acetylation of an amino acid residue of a peptide or protein, according to the reaction: acetyl-CoA + peptide = CoA + N-acetylpeptide.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: peptide alpha-N-acetyltransferase activity
Acc: GO:0004596
Aspect: Molecular Function
Desc: Catalysis of the acetylation of the N-terminal amino acid residue of a peptide or protein, according to the reaction: acetyl-CoA + peptide = CoA + N-alpha-acetylpeptide.
Synonyms:
  • acetyl-CoA:peptide alpha-N-acetyltransferase activity
  • peptide acetyltransferase activity
  • acetyl-CoA:peptide nalpha-acetyltransferase activity
  • N(alpha)-acetyltransferase activity
  • beta-endorphin acetyltransferase activity
  • nalpha-acetyltransferase activity
  • protein N-terminal acetyltransferase activity
  • NAT activity
  • amino-terminal amino acid-acetylating enzyme activity
Proteins in PDR annotated with:
   This term: 28 [Search]
   Term or descendants: 40 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004596 - peptide alpha-N-acetyltransferase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle