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Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. Catalysis of the reaction: NADPH + H+ + quinone acceptor = NADP+ + hydroquinone. Catalysis of the reaction: NADPH + H+ + acceptor = NADP+ + reduced acceptor.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: NADPH dehydrogenase activity
Acc: GO:0003959
Aspect: Molecular Function
Desc: Catalysis of the reaction: NADPH + H+ + quinone acceptor = NADP+ + hydroquinone.
Synonyms:
  • triphosphopyridine diaphorase activity
  • NADPH:acceptor oxidoreductase activity
  • triphosphopyridine nucleotide diaphorase activity
  • old yellow enzyme
  • NADPH2-dehydrogenase activity
  • TPNH-diaphorase activity
  • GO:0008468
  • NADPH2 diaphorase activity
  • NADPH-dehydrogenase activity
  • reduced nicotinamide adenine dinucleotide phosphate dehydrogenase activity
  • NADPH:(acceptor) oxidoreductase activity
  • NADPH diaphorase activity
  • TPNH dehydrogenase activity
  • GO:0016660
  • dihydronicotinamide adenine dinucleotide phosphate dehydrogenase activity
  • OYE
Proteins in PDR annotated with:
   This term: 12 [Search]
   Term or descendants: 18 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0003959 - NADPH dehydrogenase activity (interactive image map)

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