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The process by which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules. The process by which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules. The process by which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class I molecule. Class I here refers to classical class I molecules. The process by which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
Acc: GO:0002479
Aspect: Biological Process
Desc: The process by which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class I molecule. Class I here refers to classical class I molecules.
Synonyms:
  • TAP-dependent exogenous peptide antigen processing and presentation via MHC class I
  • cross-presentation
  • cross presentation
  • exogenous peptide antigen processing and presentation via MHC class I, TAP-dependent
  • TAP-dependent antigen processing and presentation of exogenous peptide antigen via MHC class I
Proteins in PDR annotated with:
   This term: 2 [Search]
   Term or descendants: 2 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0002479 - antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (interactive image map)
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Created and Maintained by: Michael Riffle