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The process whereby a relatively unspecialized T cell acquires specialized features of a mature CD8-positive, alpha-beta T cell. The process whereby a precursor cell type acquires the specialized features of an alpha-beta T cell. The process whereby an antigenically nave T cell acquires the specialized features of an effector, regulatory, or memory T cell during an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells. The process whereby an antigenically nave alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell during an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells. The process whereby an antigenically nave CD8-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell during an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells. The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: CD8-positive, alpha-beta T cell differentiation during immune response
Acc: GO:0002302
Aspect: Biological Process
Desc: The process whereby an antigenically nave CD8-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell during an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.
Synonyms:
  • CD8-positive, alpha-beta T-lymphocyte differentiation during immune response
  • CD8-positive, alpha-beta T lymphocyte differentiation during immune response
  • CD8-positive, alpha-beta T-cell differentiation during immune response
Proteins in PDR annotated with:
   This term: 1 [Search]
   Term or descendants: 1 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0002302 - CD8-positive, alpha-beta T cell differentiation during immune response (interactive image map)
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