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The chemical reactions and pathways involving tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases, the function of which has not been completely established. Any process that results in the conversion of one or more primary non-coding RNA (ncRNA) transcripts into one or more mature ncRNA molecules. Generation of the mature 5'-end of the tRNA, usually via an endonucleolytic cleavage by RNase P. The process by which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: tRNA 5'-leader removal
Acc: GO:0001682
Aspect: Biological Process
Desc: Generation of the mature 5'-end of the tRNA, usually via an endonucleolytic cleavage by RNase P.
Synonyms:
  • tRNA 5' leader removal
Proteins in PDR annotated with:
   This term: 12 [Search]
   Term or descendants: 12 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0001682 - tRNA 5'-leader removal (interactive image map)
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Created and Maintained by: Michael Riffle