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The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione. The chemical reactions and pathways resulting in the breakdown of lipoic acid, 1,2-dithiolane-3-pentanoic acid, a coenzyme involved in oxidative decarboxylation of keto acids. The chemical reactions and pathways involving lipoate, 1,2-dithiolane-3-pentanoate, the anion derived from lipoic acid. The chemical reactions and pathways involving lipoic acid, 1,2-dithiolane-3-pentanoic acid, a coenzyme involved in oxidative decarboxylation of keto acids. The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons). The chemical reactions and pathways involving a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate. The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-). The chemical reactions and pathways involving lipoamide, the functional form of lipoic acid in which the carboxyl group is attached to protein by an amide linkage to a lysine amino group. The chemical reactions and pathways by which individual cells transform chemical substances. The chemical reactions and pathways resulting in the formation of lipoic acid, 1,2-dithiolane-3-pentanoic acid, a coenzyme involved in oxidative decarboxylation of keto acids. The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings). The chemical reactions and pathways involving coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: lipoic acid metabolic process
Acc: GO:0000273
Aspect: Biological Process
Desc: The chemical reactions and pathways involving lipoic acid, 1,2-dithiolane-3-pentanoic acid, a coenzyme involved in oxidative decarboxylation of keto acids.
Synonyms:
  • lipoic acid metabolism
Proteins in PDR annotated with:
   This term: 1 [Search]
   Term or descendants: 47 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0000273 - lipoic acid metabolic process (interactive image map)
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