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Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules. A SWI/SNF-type complex that is found in post-mitotic neurons, and in human contains actin and proteins encoded by the ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, DPF1/BAF45B, DPF3/BAF45C, ACTL6B/BAF53B genes. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth. A chromatin remodeling complex that contains an ortholog of the Saccharomyces ATPase Swi2/Snf2 as one of the core components. A SWI/SNF-type complex that contains the ATPase product of the mammalian BAF180 gene. A SWI/SNF-type complex that contains nine or more proteins, including both conserved (core) and nonconserved components; the Swi2/Snf2 ATPase is one of the core components. Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. A SWI/SNF-type complex that contains the ATPase product of the Drosophila brahma gene, or an ortholog thereof. Any complex that mediates dynamic changes in eukaryotic chromatin. A SWI/SNF-type complex that is found in neural stem or progenitor cells, and in human contains actin and proteins encoded by the ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, PHF10/BAF45A, ACTL6A/BAF53A genes. The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: SWI/SNF-type complex
Acc: GO:0070603
Aspect: Cellular Component
Desc: A chromatin remodeling complex that contains an ortholog of the Saccharomyces ATPase Swi2/Snf2 as one of the core components.
Synonyms:
  • SWI-SNF global transcription activator complex
  • SWI-SNF-type complex
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 94 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0070603 - SWI/SNF-type complex (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle