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The process whereby the developmental fate of a cell becomes restricted such that it will develop into an epithelial cell. The commitment of a cell to an endothelial cell fate and its capacity to differentiate into an endothelial cell. The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. The process involved in the specification of cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition. The process whereby a mesodermal angioblast acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium. The process involved in the specification of identity of an endothelial cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: endothelial cell fate specification
Acc: GO:0060847
Aspect: Biological Process
Desc: The process involved in the specification of identity of an endothelial cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.
Proteins in PDR annotated with:
   This term: 1 [Search]
   Term or descendants: 1 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0060847 - endothelial cell fate specification (interactive image map)

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