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The commitment of a venous blood vessel endothelial cell to a lymphatic endothelial cell fate and its capacity to differentiate into a lymphatic endothelial cell. The process whereby a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium. The process whose specific outcome is the progression of an endothelium over time, from its formation to the mature structure. An endothelium is an epithelium that lines an anatomical structure. The process whereby a mesodermal angioblast acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium. The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. The process whose specific outcome is the progression of the lymphatic vasculature over time, from its formation to the mature structure. The process whereby a venous blood vessel endothelial cell acquires specialized features of a lymphatic vessel endothelial cell, a thin flattened cell that lines the inside surfaces of lymph vessels. The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: lymphatic endothelial cell differentiation
Acc: GO:0060836
Aspect: Biological Process
Desc: The process whereby a venous blood vessel endothelial cell acquires specialized features of a lymphatic vessel endothelial cell, a thin flattened cell that lines the inside surfaces of lymph vessels.
Proteins in PDR annotated with:
   This term: 3 [Search]
   Term or descendants: 4 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0060836 - lymphatic endothelial cell differentiation (interactive image map)
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