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Any process that modulates the frequency, rate or extent of phagocytosis, the process whereby phagocytes engulf external particulate material. The process whereby phagocytes engulf external particulate material. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles. Any process that stops, prevents or reduces the frequency, rate or extent of phagocytosis. Any process that stops, prevents or reduces the frequency, rate or extent of endocytosis. The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis. Any process that stops, prevents or reduces the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis. Any process that modulates the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis. The infolding of a membrane, resulting in formation of a vesicle.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of phagocytosis, engulfment
Acc: GO:0060101
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.
Proteins in PDR annotated with:
   This term: 1 [Search]
   Term or descendants: 1 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0060101 - negative regulation of phagocytosis, engulfment (interactive image map)
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