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The process whereby a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. Process involved in cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment. A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition. The process whereby a cell becomes capable of differentiating autonomously into a satellite cell regardless of its environment; upon determination, the cell fate cannot be reversed. The process whereby the developmental fate of a cell becomes restricted such that it will develop into a stem cell. The process whereby a cell becomes capable of differentiating autonomously into a stem cell regardless of its environment; upon determination, the cell fate cannot be reversed.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: stem cell fate determination
Acc: GO:0048867
Aspect: Biological Process
Desc: The process whereby a cell becomes capable of differentiating autonomously into a stem cell regardless of its environment; upon determination, the cell fate cannot be reversed.
Proteins in PDR annotated with:
   This term: 1 [Search]
   Term or descendants: 1 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0048867 - stem cell fate determination (interactive image map)
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Created and Maintained by: Michael Riffle