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Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells. The process of targeting specific proteins to particular membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif. Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of a protein into, out of, within or between cells by means of some external agent such as a transporter or pore. The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell. The directed movement of molecules between the nucleus and the cytoplasm. Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of proteins from the nucleus into the cytoplasm. Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells. The directed movement of a protein from the nucleus into the cytoplasm. Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells. Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of substances between the cytoplasm and the nucleus. The directed movement of substances out of the nucleus. Any process that modulates the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm. Any process that modulates the frequency, rate or extent of the directed movement of proteins from the nucleus to the cytoplasm.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of protein export from nucleus
Acc: GO:0046826
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of proteins from the nucleus into the cytoplasm.
Synonyms:
  • down regulation of protein export from nucleus
  • down-regulation of protein export from nucleus
  • inhibition of protein export from nucleus
  • negative regulation of protein transport from nucleus to cytoplasm
  • negative regulation of protein export from cell nucleus
  • downregulation of protein export from nucleus
  • negative regulation of protein export out of nucleus
  • negative regulation of protein-nucleus export
Proteins in PDR annotated with:
   This term: 5 [Search]
   Term or descendants: 5 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0046826 - negative regulation of protein export from nucleus (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle