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Any process that stops, prevents, or reduces the rate of leukocyte degranulation. Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or group of cells. Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of a substance from a cell or group of cells. Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell. This is the process whereby most molecules are secreted from eukaryotic cells. Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. The controlled release of a substance by a cell, a group of cells, or a tissue. Any process that stops, prevents or reduces the frequency, rate or extent of exocytosis. Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion-dependent exocytosis. Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process that modulates the frequency, rate or extent of exocytosis. Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell. The directed movement of substances into, out of or within a cell by a cellular process that begins with the formation of membrane-bounded vesicles in which the transported substances are enclosed or located in the vesicle membrane. Vesicles are then targeted to, and fuse with, an acceptor membrane. The controlled release of a substance by a cell. Any process that modulates the frequency, rate or extent of a process by which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell. Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells by means of some external agent such as a transporter or pore.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of exocytosis
Acc: GO:0045920
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of exocytosis.
Synonyms:
  • inhibition of exocytosis
  • downregulation of exocytosis
  • down-regulation of exocytosis
  • down regulation of exocytosis
Proteins in PDR annotated with:
   This term: 3 [Search]
   Term or descendants: 10 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0045920 - negative regulation of exocytosis (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle