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Any process that mediates the adoption of a specific fate by a cell. Any process that stops, prevents or reduces the frequency, rate or extent of axial mesoderm cell fate specification. The process involved in the specification of cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. Any process that restricts, stops or prevents a cell from adopting a specific cell fate. Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm cell fate specification. The process by which a cell becomes committed to become part of the mesoderm. Any process that modulates the frequency, rate or extent of mesoderm cell fate specification. Process by which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. Any process that stops, prevents or reduces the frequency, rate or extent of paraxial mesoderm cell fate specification. Any process that stops, prevents or reduces the frequency, rate or extent of lateral mesoderm cell fate specification. Any process that stops, prevents or reduces the frequency, rate or extent of intermediate mesoderm cell fate specification.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of mesodermal cell fate specification
Acc: GO:0042662
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm cell fate specification.
Synonyms:
  • down regulation of mesodermal cell fate specification
  • down-regulation of mesodermal cell fate specification
  • inhibition of mesodermal cell fate specification
  • suppression of mesodermal cell fate
  • downregulation of mesodermal cell fate specification
Proteins in PDR annotated with:
   This term: 2 [Search]
   Term or descendants: 2 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0042662 - negative regulation of mesodermal cell fate specification (interactive image map)
YRC Informatics Platform - Version 3.0
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