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The process whereby a relatively unspecialized cell acquires specialized features of a neuromast hair cell. Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons. The process whereby relatively unspecialized cells, acquire specialized structural and/or functional features of inner ear receptor cells. Inner ear receptor cells are mechanorecptors found in the inner ear responsible for transducing signals involved in balance and sensory perception of sound. The process whereby a relatively unspecialized cell acquires specialized features of a mechanoreceptor, a cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system. The process whereby a relatively unspecialized cell acquires specialized features of a neuron. The process by which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons. Any process that modulates the frequency, rate or extent of mechanoreceptor differentiation. Differentiation of new mechanoreceptors to replace those lost or destroyed by injury. Any process that activates or increases the frequency, rate or extent of mechanoreceptor differentiation. The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. Any process that stops, prevents or reduces the frequency, rate or extent of mechanoreceptor differentiation.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: mechanoreceptor differentiation
Acc: GO:0042490
Aspect: Biological Process
Desc: The process whereby a relatively unspecialized cell acquires specialized features of a mechanoreceptor, a cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system.
Proteins in PDR annotated with:
   This term: 15 [Search]
   Term or descendants: 69 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0042490 - mechanoreceptor differentiation (interactive image map)
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