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The developmental process pertaining to the initial formation of an epithelial tube. Creation of the central hole of a tube in an anatomical structure by sealing the edges of an epithelial fold. A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition. The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. Creation of the central hole of a tube in an open tracheal system through which gases flow. The process by which the anatomical structures of a tube are generated and organized. Morphogenesis pertains to the creation of form. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system. Creation of the central hole of a tube in an anatomical structure through which gases and/or liquids flow. The process whose specific outcome is the progression of a tube over time, from its initial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts. The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form. The formation of a lumen by hollowing out a solid rod or cord.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: tube formation
Acc: GO:0035148
Aspect: Biological Process
Desc: Creation of the central hole of a tube in an anatomical structure through which gases and/or liquids flow.
Synonyms:
  • tube lumen formation
  • lumen formation in an anatomical structure
Proteins in PDR annotated with:
   This term: 6 [Search]
   Term or descendants: 162 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0035148 - tube formation (interactive image map)
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