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A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. The assembly of chromatin into heterochromatin near the centromere. Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin, a compact and highly condensed form of chromatin. The assembly of chromatin into heterochromatin, a compact and highly condensed form that is often, but not always, transcriptionally silent. The assembly of DNA, histone proteins, and other associated proteins into chromatin structure, beginning with the formation of the basic unit, the nucleosome, followed by organization of the nucleosomes into higher order structures, ultimately giving rise to a complex organization of specific domains within the nucleus. Dynamic structural changes in centromeric DNA. Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation. The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex. The aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex. Includes the formation of the chromatin structures which form a platform for the kinetochore, and assembly of the kinetochore onto this specialized chromatin. In fission yeast and higher eukaryotes this process also includes the formation of heterochromatin at the outer repeat (pericentric) regions of the centromere.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: centromeric heterochromatin formation
Acc: GO:0031508
Aspect: Biological Process
Desc: The assembly of chromatin into heterochromatin near the centromere.
Synonyms:
  • centric heterochromatin formation
  • centromeric heterochromatin assembly
  • centromeric heterochromatin biosynthesis
Proteins in PDR annotated with:
   This term: 3 [Search]
   Term or descendants: 3 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0031508 - centromeric heterochromatin formation (interactive image map)
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