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The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin moiety, or multiple ubiquitin moieties, to the protein. The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent modification of the target protein. The series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand. The chemical reactions and pathways resulting in the breakdown of SMAD signaling proteins by ubiquitination and targeting to the proteasome. Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell, where the receptor possesses catalytic activity or is closely associated with an enzyme such as a protein kinase.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: ubiquitin-dependent SMAD protein catabolic process
Acc: GO:0030579
Aspect: Biological Process
Desc: The chemical reactions and pathways resulting in the breakdown of SMAD signaling proteins by ubiquitination and targeting to the proteasome.
Synonyms:
  • ubiquitin-dependent SMAD protein degradation
  • ubiquitin-dependent SMAD protein catabolism
  • ubiquitin-dependent SMAD protein breakdown
Proteins in PDR annotated with:
   This term: 4 [Search]
   Term or descendants: 4 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0030579 - ubiquitin-dependent SMAD protein catabolic process (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle