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Catalysis of the transfer of a hydroxyl group from 2-oxoglutarate to a prolyl residue in a protein. Catalysis of the transfer of a hydroxyl group from 2-oxoglutarate to a prolyl residue in a collagen molecule. Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = procollagen trans-3-hydroxy-L-proline + succinate + CO2. Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-3-hydroxy-L-proline + succinate + CO2.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: procollagen-proline 3-dioxygenase activity
Acc: GO:0019797
Aspect: Molecular Function
Desc: Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-3-hydroxy-L-proline + succinate + CO2.
Synonyms:
  • proline,2-oxoglutarate 3-dioxygenase activity
  • procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity
  • procollagen-proline,2-oxoglutarate 3-dioxygenase activity
  • prolyl 3-hydroxylase activity
  • prolyl-4-hydroxyprolyl-glycyl-peptide, 2-oxoglutarate: oxygen oxidoreductase, 3-hydroxylating activity
  • protocollagen proline 3-hydroxylase activity
Proteins in PDR annotated with:
   This term: 3 [Search]
   Term or descendants: 3 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0019797 - procollagen-proline 3-dioxygenase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle