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Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water. Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor. Catalysis of the reaction: protein N6-(4-aminobutyl)-L-lysine + donor-H2 + O2 = protein N6-((R)-4-amino-2-hydroxybutyl)-L-lysine + acceptor + H2O.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: deoxyhypusine monooxygenase activity
Acc: GO:0019135
Aspect: Molecular Function
Desc: Catalysis of the reaction: protein N6-(4-aminobutyl)-L-lysine + donor-H2 + O2 = protein N6-((R)-4-amino-2-hydroxybutyl)-L-lysine + acceptor + H2O.
Synonyms:
  • deoxyhypusine,hydrogen-donor:oxygen oxidoreductase (2-hydroxylating)
  • DOHH activity
  • deoxyhypusine hydroxylase activity
  • deoxyhypusine dioxygenase activity
Proteins in PDR annotated with:
   This term: 7 [Search]
   Term or descendants: 7 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0019135 - deoxyhypusine monooxygenase activity (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle