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Catalysis of the reaction: trans-geranyl-CoA = cis-geranyl-CoA. Catalysis of the isomerization of poly-cis-carotenoids to all-trans-carotenoids. Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0). Catalysis of the reaction: all-trans-retinol = 11-cis-retinol. Catalysis of the reaction: cis-2-chloro-4-carboxymmethylenebut-2-en-1,4-olide = trans-2-chloro-4-carboxymmethylenebut-2-en-1,4-olide. Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. Catalysis of the reaction: (E)-4-hydroxyphenylacetaldehyde oxime = (Z)-4-hydroxyphenylacetaldehyde oxime. Catalysis of the reaction: maleate = fumarate. Catalysis of the reaction: 3-maleylpyruvate = 3-fumarylpyruvate. Catalysis of the reaction: cis-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate = trans-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate. Catalysis of the reaction: 9-cis,12-cis-octadecadienoate = 9-cis,11-trans-octadecadienoate. Catalysis of the reaction: (E)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide = (Z)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide. Catalysis of the reaction: 4-maleylacetoacetate = 4-fumarylacetoacetate. Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5. Catalysis of the reaction: 2-trans,6-trans-farnesol = 2-cis,6-trans-farnesol. Catalysis of a reaction that interconverts cis and trans isomers. Atoms or groups are termed cis or trans to one another when they lie respectively on the same or on opposite sides of a reference plane identifiable as common among stereoisomers. Catalysis of the reaction: all-trans-retinal = 11-cis-retinal.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: cis-trans isomerase activity
Acc: GO:0016859
Aspect: Molecular Function
Desc: Catalysis of a reaction that interconverts cis and trans isomers. Atoms or groups are termed cis or trans to one another when they lie respectively on the same or on opposite sides of a reference plane identifiable as common among stereoisomers.
Proteins in PDR annotated with:
   This term: 1 [Search]
   Term or descendants: 331 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0016859 - cis-trans isomerase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle