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Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the delta-nitrogen atom of peptidyl-arginine residues. Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to an amino group of an arginine residue. Catalysis of the transfer of a methyl group to an acceptor molecule. Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to an amino group of an arginine residue in a protein substrate. Catalysis of the addition of a methyl group to either of the unmethylated terminal nitrogen atoms (also called omega nitrogen) in peptidyl-arginine to form an omega-N-G-monomethylated arginine residue. Catalysis of the reaction: S-adenosyl-L-methionine + (cytochrome c)-arginine = S-adenosyl-L-homocysteine + (cytochrome c)-N(omega)-methyl-arginine. Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate. Catalysis of the reaction: S-adenosyl-L-methionine + (myelin basic protein)-arginine = S-adenosyl-L-homocysteine + (myelin basic protein)-N(omega)-methyl-arginine. Catalysis of the transfer of a methyl group to the nitrogen atom of an acceptor molecule. Catalysis of the reaction: S-adenosyl-L-methionine + histone-arginine = S-adenosyl-L-homocysteine + histone-N-methyl-arginine. Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the terminal nitrogen (omega nitrogen) residue that is not already methylated, resulting in symmetrical peptidyl-N(omega),N'(omega)-dimethyled arginine residues. Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the same terminal nitrogen (omega nitrogen) residue that was previously methylated, resulting in asymmetrical peptidyl-N(omega),N(omega)-dimethylated arginine residues. Catalysis of the transfer of a methyl group (CH3-) to a protein.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: protein-arginine N-methyltransferase activity
Acc: GO:0016274
Aspect: Molecular Function
Desc: Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to an amino group of an arginine residue in a protein substrate.
Synonyms:
  • PRMT activity
Proteins in PDR annotated with:
   This term: 25 [Search]
   Term or descendants: 43 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0016274 - protein-arginine N-methyltransferase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle