YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Any process that stops, prevents or reduces the frequency, rate or extent of a response to nutrient levels. Any process that stops, prevents or reduces the frequency, rate or extent of macroautophagy. Any process that modulates the frequency, rate or extent of macroautophagy. The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane-bounded autophagic bodies which are then degraded within the lysosome (or vacuole). Though once thought to be a purely non-selective process, it appears that some types of macroautophagy, e.g. macropexophagy, macromitophagy, may involve selective targeting of the targets to be degraded. The process by which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation. Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process that stops, prevents or reduces the frequency, rate or extent of a response to an extracellular stimulus. Any process that modulates the frequency, rate or extent of a response to nutrient levels. Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. Any process that stops, prevents or reduces the frequency, rate or extent of autophagy. Autophagy is the process by which cells digest parts of their own cytoplasm. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients. Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process by which cells digest parts of their own cytoplasm. A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment. Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of macroautophagy
Acc: GO:0016242
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of macroautophagy.
Synonyms:
  • downregulation of macroautophagy
  • negative regulation of starvation-induced autophagy
  • down regulation of macroautophagy
  • down-regulation of macroautophagy
  • inhibition of macroautophagy
Proteins in PDR annotated with:
   This term: 3 [Search]
   Term or descendants: 3 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0016242 - negative regulation of macroautophagy (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle