YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Catalysis of the transfer of spermine from one side of the membrane to the other. Spermine is a polybasic amine found in human sperm, in ribosomes and in some viruses, which is involved in nucleic acid packaging. Synthesis is regulated by ornithine decarboxylase which plays a key role in control of DNA replication. Catalysis of the transfer of putrescine from one side of the membrane to the other. Putrescine is 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine. Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + polyamine(in) = H+(in) + polyamine(out). Catalysis of the reaction: ATP + H2O + polyamine(out) = ADP + phosphate + polyamine(in). Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other. Catalysis of the transfer of spermidine, N-(3-aminopropyl)-1,4-diaminobutane, from one side of the membrane to the other. Catalysis of the transfer of amines, including polyamines, from one side of the membrane to the other. Amines are organic compounds that are weakly basic in character and contain an amino (-NH2) or substituted amino group. Catalysis of the transfer of polyamines, organic compounds containing two or more amino groups, from one side of the membrane to the other. Catalysis of the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: polyamine transmembrane transporter activity
Acc: GO:0015203
Aspect: Molecular Function
Desc: Catalysis of the transfer of polyamines, organic compounds containing two or more amino groups, from one side of the membrane to the other.
Synonyms:
  • amine/amide/polyamine channel activity
Proteins in PDR annotated with:
   This term: 16 [Search]
   Term or descendants: 135 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0015203 - polyamine transmembrane transporter activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle