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The directed movement of acetylcholine into, out of, within or between cells by means of some external agent such as a transporter or pore. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions. Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of a substance from a cell or group of cells. Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell or group of cells. The regulated release of acetylcholine by a cell or group of cells. The acetylcholine is a neurotransmitter that acts in both the peripheral nervous system (PNS) and central nervous system (CNS). Any process that modulates the frequency, rate or extent of the regulated release of acetylcholine. The regulated release of neurotransmitter into the synaptic cleft. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma-aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin. Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of a neurotransmitter. Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of acetylcholine. The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of, within or between cells by means of some external agent such as a transporter or pore. Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of amines into, out of, within or between cells by means of some external agent such as a transporter or pore. Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into, out of, within or between cells by means of some external agent such as a transporter or pore. Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of, within or between cells by means of some external agent such as a transporter or pore. Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells by means of some external agent such as a transporter or pore.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of acetylcholine secretion
Acc: GO:0014058
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of acetylcholine.
Synonyms:
  • down regulation of acetylcholine secretion
  • down-regulation of acetylcholine secretion
  • downregulation of acetylcholine secretion
  • inhibition of acetylcholine secretion
Proteins in PDR annotated with:
   This term: 2 [Search]
   Term or descendants: 2 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0014058 - negative regulation of acetylcholine secretion (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle