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Any process that stops, prevents or reduces the frequency, rate or extent of a signaling pathway. Any process that decreases the rate, frequency, or extent of SMAD protein complex assembly. SMAD protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex that contains SMAD proteins. Any process that modulates the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand. Any process that modulates the rate, frequency, or extent of SMAD protein complex assembly. SMAD protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex that contains SMAD proteins. The aggregation, arrangement and bonding together of a set of components to form a protein complex, occurring at the level of an individual cell. The aggregation, arrangement and bonding together of a set of components to form a protein complex that contains SMAD proteins. The aggregation, arrangement and bonding together of a set of components to form a protein complex. Any process that stops, prevents or reduces the frequency, rate or extent of protein complex assembly. Any process that stops, prevents or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process that modulates the frequency, rate or extent of protein complex assembly. The series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand. Any process that decreases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of SMAD protein complex assembly
Acc: GO:0010991
Aspect: Biological Process
Desc: Any process that decreases the rate, frequency, or extent of SMAD protein complex assembly. SMAD protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex that contains SMAD proteins.
Proteins in PDR annotated with:
   This term: 3 [Search]
   Term or descendants: 3 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0010991 - negative regulation of SMAD protein complex assembly (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle