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Inhibition of the reactions brought about by dioxygen (O2) or peroxides. Usually the antioxidant is effective because it can itself be more easily oxidized than the substance protected. The term is often applied to components that can trap free radicals, thereby breaking the chain reaction that normally leads to extensive biological damage. Catalysis of the reaction: donor + H2O2 = oxidized donor + 2 H2O. Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor. Catalysis of the reaction: 2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH. Catalysis of an oxidation-reduction (redox) reaction in which the peroxide group acts as a hydrogen or electron acceptor. Catalysis of the reaction: thioredoxin + H2O2 = thioredoxin disulfide + H2O.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: thioredoxin peroxidase activity
Acc: GO:0008379
Aspect: Molecular Function
Desc: Catalysis of the reaction: thioredoxin + H2O2 = thioredoxin disulfide + H2O.
Synonyms:
  • GO:0009031
  • thiol peroxidase activity
  • TPx activity
  • TrxPx activity
Proteins in PDR annotated with:
   This term: 41 [Search]
   Term or descendants: 41 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0008379 - thioredoxin peroxidase activity (interactive image map)
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