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Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein. The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells. The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with the hydrolysis of peptide bonds. Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein. The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification. Any process that stops, prevents or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein. The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: proteolysis
Acc: GO:0006508
Aspect: Biological Process
Desc: The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with the hydrolysis of peptide bonds.
Synonyms:
  • peptidolysis
  • ATP-dependent proteolysis
Proteins in PDR annotated with:
   This term: 3454 [Search]
   Term or descendants: 5043 [Refine Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0006508 - proteolysis (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle